Typhoid fever is primarily caused by which organism?

Typhoid fever is primarily caused by the bacterium Salmonella typhi. This organism is a type of Salmonella that is specific to humans and is responsible for the systemic infection that characterizes typhoid fever. Infection typically occurs through ingestion of contaminated food or water, leading to symptoms such as prolonged fever, abdominal pain, and gastrointestinal disturbances.

Salmonella typhi has evolved specific mechanisms to evade the host's immune response, allowing it to multiply and spread within the body. Understanding the connection between this bacterium and typhoid fever is crucial for diagnosing and treating the illness effectively, as well as implementing preventive measures such as vaccination in high-risk areas.