What condition is characterized by discontinuity of the lumen and is associated with bile-containing vomitus?

Duodenal atresia is a condition where there is a complete obstruction of the duodenum, which results in a discontinuity of the lumen of the intestine. This leads to the inability of the normal passage of food and digestive contents beyond the blockage. One of the key clinical signs associated with duodenal atresia is the presence of bile-containing vomitus. This occurs because the obstruction prevents the downstream passage of contents, and the material may back up, including bile that is produced in the liver and usually flows into the duodenum.

This condition is often identified in newborns and is sometimes associated with other congenital anomalies. The classic "double bubble" sign on X-rays is a characteristic radiological finding, showing a distended stomach and duodenum without the presence of gas in the distal bowel.

Other conditions listed, such as Meckel's diverticulum and celiac disease, do not typically present with bile-containing vomitus due to the different underlying mechanisms of obstruction or malabsorption. Superior mesenteric artery syndrome involves compression of the duodenum but is not characterized by complete discontinuity of the lumen. Each of these conditions has unique clinical presentations and implications that set them apart from duodenal atresia.