What is the consequence of pancreatic enzyme deficiency in cystic fibrosis?

Pancreatic enzyme deficiency in cystic fibrosis leads to malabsorption due to the lack of digestive enzymes that are essential for breaking down nutrients in the intestines. In cystic fibrosis, thick mucus obstructs the pancreatic ducts, preventing enzymes like lipase, amylase, and proteases from reaching the small intestine. As a result, the body struggles to absorb fats, proteins, and carbohydrates effectively from the diet, leading to poor nutritional status and failure to thrive in affected individuals. This malabsorption can also result in greasy, bulky stools and deficiencies in fat-soluble vitamins (A, D, E, and K), which can further complicate the health of those with cystic fibrosis. The other options, while possible consequences related to cystic fibrosis, do not directly stem from the pancreatic enzyme deficiency in the same way that malabsorption does.