Where is the endocrine secretion of the pancreas primarily produced?

The endocrine secretion of the pancreas is primarily produced in the Islets of Langerhans. These specialized clusters of cells are scattered throughout the pancreas and are responsible for the production of hormones such as insulin and glucagon, which play crucial roles in regulating blood sugar levels. The islets contain various types of cells: alpha cells produce glucagon, beta cells produce insulin, and delta cells produce somatostatin, among others.

The other parts of the pancreas, such as the head and body, are primarily involved in exocrine functions, which include the production of digestive enzymes that are secreted into the pancreatic duct and then into the small intestine to aid in digestion. The pancreatic duct itself is responsible for transporting these digestive enzymes, not for hormone production. Therefore, the Islets of Langerhans represent the specific region where the endocrine function of the pancreas is localized.