Which demographic is most likely to suffer from superior mesenteric artery syndrome (cast syndrome)?

The demographic most likely to suffer from superior mesenteric artery syndrome, often referred to as cast syndrome, is young ladies. This condition typically occurs when the duodenum is compressed between the superior mesenteric artery and the aorta, often due to various anatomical or physiological changes.

Young women, particularly those who may experience significant weight loss or have a low body mass index, are disproportionately affected by this syndrome. Factors contributing to this demographic's vulnerability include lifestyle trends, such as those related to dieting or eating disorders, which can lead to changes in body composition, and the anatomy of the female pelvis. This can create a narrower angle between the aorta and the superior mesenteric artery, increasing the risk of duodenal obstruction.

In summary, the heightened risk among young ladies is linked to both anatomical predispositions and lifestyle factors that can lead to the specific physiological changes associated with superior mesenteric artery syndrome.